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trans-3-Indoleacrylic acid

CAS No. 29953-71-7

trans-3-Indoleacrylic acid( trans-IAA )

Catalog No. M20033 CAS No. 29953-71-7

trans-3-Indoleacrylic acid is a Tryptophan metabolite.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    trans-3-Indoleacrylic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    trans-3-Indoleacrylic acid is a Tryptophan metabolite.
  • Description
    trans-3-Indoleacrylic acid is a Tryptophan metabolite.
  • In Vitro
    Cell Viability Assay Cell Line:HT29, HT1080 Concentration:5-500 μM Incubation Time:24 h Result:Inhibited ferroptosis in HT29 and HT1080, with presence of AHR or FSP1.
  • In Vivo
    Animal Model:HT29 tumor-bearing xenograft nu/nu mice Dosage:50 mg/kg Administration:Intraperitoneal injection, three times a week Result:Promoted tumor growth with deficiency of AHR or FSP1.
  • Synonyms
    trans-IAA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    29953-71-7
  • Formula Weight
    187.19
  • Molecular Formula
    C11H9NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:197.7 mM
  • SMILES
    OC(=O)\C=C\c1c[nH]c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jin G. Lee S. Choi M. Son S. Kim G. & Oh J. et al. (2014). Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.?European Journal Of Medicinal Chemistry?75 413-425. doi: 10.1016/j.ejmech.2014.01.062
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